Treatment Of Acute Myeloid Leukemia - Hanging On To Life

Acute myeloid leukemia is a heterogeneous cancer of the Bloodstream and bone marrow. This tumor occurs
as a result of an More than production of immature Whitened Bloodstream cell which is called myeloblast.

The name of the disease is gotten from the Bloodstream cell produced in excess. The immature Whitened Bloodstream
cell produced Becomes into the bone marrow and it's More than production hinders the production of the
normal Bloodstream Tissues.

The main cause of the display of these symptoms is as a result of the The loss of normal function of
Bloodstream by these myelobast. Because they are immature and reduce the mature and proper functioning
Bloodstream, their function as Bloodstream Tissues is greatly reduced. One of the functions of Bloodstream affected in
acute myeloid leukemia is fighting Versus Virus.

Patients with acute myeloid leukemia are easily infected due to reduced immunity Versus
Virus. Another very Typical symptom in Clients suffering from acute myeloid leukemia is
anemia. Anemia is as a result of reduced production of normal red Bloodstream Tissues and platelets.
Anemia is usually Serious with Unique Degrees of severity seen in Unique Clients. Acute
myeloid leukemia has other symptoms like being easily bruised and having swollen gum, bleeding of
the nose, fever, skin pallor and even shortness of breath.

The Remedy of acute myeloid leukemia in a newly diagnosed Client consist of chemotherapy ( the
type of chemotherapy used is age dependent) aimed to quickly induce total remission, when this is
achieved, further therapy is then aimed at Remedy of the disease (by eliminating any undetected
residuals of the leukemic Tissues). Therefore the Remedy process is divided into two Phases.

The first Phase is the Phase of induction. The goal of this therapy is to get complete remission
by reducing the quantity of the leukemic Tissues in the bone marrow and circulating Bloodstream to an
undetectable Degree. The Typically used complete remission induction is a combined chemotherapy of
cytarabine and anthracycline. Cytarabine is administered intravenously with dosage of 100 -
200mg/m2/day for one week. Anthracycline consists of daunorubicin is administered intravenously
45-60mg/m2 on day1, 2, and 3.

When induction therapy is completed, the bone marrow is examined. If blast Tissues are more than 5%
with up to 20% cellular Tissues, induction therapy is performed again with dose similar to the first
but cytarabine is given for 5 and antracycline 2 days. But after the second therapy if there is no
positive result stem cell transplant is considered, though this is only possible in Client
More youthful than 65 years.

The second Phase is post remission or consolidation therapy, which is aimed at Remedy of Clients
with acute myeloid leukemia after the leukemic Tissues Gets undetectable. In this therapy
Remedy is based on the Client's condition, this therapy involves an additional intensive
chemotherapy of 3 to 5 courses. Patients with Higher Chance of cytogenetics are given allogeneic stem
cell transplant. Patients who stem cell transplant is not suitable for, are treated with a
combination therapy of histamine dihydrochloride (ceplene) and interleukin 2.

The Remedy of acute myeloid leukemia has Proven good prognosis in the time past especially if
diagnosis is made early ant Remedy is started immediately.